姓名:唐其柱
单位:manbetx万博
人民医院心血管内科
职称:院长、教授、博导
邮箱:qztang@whu.edu.cn
联系电话:027-88073385
研究方向:
1. 心肌重构的发病机制与临床防治
2. 心肌细胞电生理与心律失常
代表性论著:
1. Ma ZG, Yuan YP, Zhang X, Xu SC, Wang SS, Tang QZ. Piperine attenuates pathological cardiac fibrosis via ppar-gamma/akt pathways. EBioMedicine. 2017;18:179-187
2. Ma ZG, Yuan YP, Xu SC, Wei WY, Xu CR, Zhang X, Wu QQ, Liao HH, Ni J, Tang QZ. Ctrp3 attenuates cardiac dysfunction, inflammation, oxidative stress and cell death in diabetic cardiomyopathy in rats. Diabetologia. 2017;60:1126-1137
3. Wu QQ, Yuan Y, Jiang XH, Xiao Y, Yang Z, Ma ZG, Liao HH, Liu Y, Chang W, Bian ZY, Tang QZ. Ox40 regulates pressure overload-induced cardiac hypertrophy and remodelling via cd4+ t-cells. Clin Sci (Lond). 2016;130:2061-2071
4. Ma ZG, Dai J, Wei WY, Zhang WB, Xu SC, Liao HH, Yang Z, Tang QZ. Asiatic acid protects against cardiac hypertrophy through activating ampkalpha signalling pathway. Int J Biol Sci. 2016;12:861-871
5. Ma ZG, Dai J, Zhang WB, Yuan Y, Liao HH, Zhang N, Bian ZY, Tang QZ. Protection against cardiac hypertrophy by geniposide involves the glp-1 receptor / ampkalpha signalling pathway. Br J Pharmacol. 2016;173:1502-1516
6. Yuan Y, Yan L, Wu QQ, Zhou H, Jin YG, Bian ZY, Deng W, Yang Z, Shen DF, Zeng XF, Wang SS, Li H, Tang QZ. Mnk1 (mitogen-activated protein kinase-interacting kinase 1) deficiency aggravates cardiac remodeling in mice. Hypertension. 2016;68:1393-1399
7. Liu Y, Hu ZF, Liao HH, Liu W, Liu J, Ma ZG, Wu QQ, Xu M, Zhang N, Zhang Y, Bian ZY, Tang QZ. Toll-like receptor 5 deficiency attenuates interstitial cardiac fibrosis and dysfunction induced by pressure overload by inhibiting inflammation and the endothelial-mesenchymal transition. Biochim Biophys Acta. 2015;1852:2456-2466
8. Zhou H, Ni J, Yuan Y, Deng W, Bian ZY, Tang QZ. Soluble st2 may possess special superiority as a risk predictor in heart failure patients. Int J Cardiol. 2015;186:146-147
9. Wu QQ, Xu M, Yuan Y, Li FF, Yang Z, Liu Y, Zhou MQ, Bian ZY, Deng W, Gao L, Li H, Tang QZ. Cathepsin b deficiency attenuates cardiac remodeling in response to pressure overload via tnf-alpha/ask1/jnk pathway. Am J Physiol Heart Circ Physiol. 2015;308:H1143-1154
10. Deng W, Wei L, Zong J, Bian Z, Zhou H, Zhang R, Tang Q. Attenuation of cardiac remodeling by indole-3-carbinol in mice is associated with improved energy metabolism. Int J Cardiol. 2014;172:e531-533
11. Bian Z, Dai J, Hiroyasu N, Guan H, Yuan Y, Gan L, Zhou H, Zong J, Zhang Y, Li F, Yan L, Shen D, Li H, Tang Q. Disruption of tumor necrosis factor receptor associated factor 5 exacerbates pressure overload cardiac hypertrophy and fibrosis. J Cell Biochem. 2014;115:349-358
12. Bian Z, Liao H, Zhang Y, Wu Q, Zhou H, Yang Z, Fu J, Wang T, Yan L, Shen D, Li H, Tang Q. Never in mitosis gene a related kinase-6 attenuates pressure overload-induced activation of the protein kinase b pathway and cardiac hypertrophy. PloS one. 2014;9:e96095
13. Dai J, Shen DF, Bian ZY, Zhou H, Gan HW, Zong J, Deng W, Yuan Y, Li F, Wu QQ, Gao L, Zhang R, Ma ZG, Li HL, Tang QZ. Ikki deficiency promotes pressure overload-induced cardiac hypertrophy and fibrosis. PloS one. 2013;8:e53412
14. Zong J, Deng W, Zhou H, Bian ZY, Dai J, Yuan Y, Zhang JY, Zhang R, Zhang Y, Wu QQ, Guo HP, Li HL, Tang QZ. 3,3'-diindolylmethane protects against cardiac hypertrophy via 5'-adenosine monophosphate-activated protein kinase-alpha2. PloS one. 2013;8:e53427
15. Zong J, Zhang DP, Zhou H, Bian ZY, Deng W, Dai J, Yuan Y, Gan HW, Guo HP, Tang QZ. Baicalein protects against cardiac hypertrophy through blocking mek-erk1/2 signaling. J Cell Biochem. 2013;114:1058-1065
16. Guan H, Chen C, Zhu L, Cui C, Guo Y, Fu M, Wang L, Tang Q. Indole-3-carbinol blocks platelet-derived growth factor-stimulated vascular smooth muscle cell function and reduces neointima formation in vivo. J Nutr Biochem. 2013;24:62-69
17. Li Y, Lu Z, Tang Q, Jiang H, Huang C, He B, Hu X, Huang J, Zhu X, Wang H. The increase in sympathetic nerve density in the atrium facilitates atrial fibrillation in patients with rheumatic heart disease. International Journal of Cardiology. 2013;165:174-178
18. Deng W, Zong J, Bian Z, Zhou H, Yuan Y, Zhang R, Guo H, Zhang Y, Shen D, Li H, Tang Q. Indole-3-carbinol protects against pressure overload induced cardiac remodeling via activating ampk-alpha. Mol Nutr Food Res. 2013;57:1680-1687
19. Zhou H, Bian ZY, Zong J, Deng W, Yan L, Shen DF, Guo H, Dai J, Yuan Y, Zhang R, Lin YF, Hu X, Li H, Tang QZ. Stem cell antigen 1 protects against cardiac hypertrophy and fibrosis after pressure overload. Hypertension. 2012;60:802-809
20. Bian ZY, Wei X, Deng S, Tang QZ, Feng J, Zhang Y, Liu C, Jiang DS, Yan L, Zhang LF, Chen M, Fassett J, Chen Y, He YW, Yang Q, Liu PP, Li H. Disruption of mindin exacerbates cardiac hypertrophy and fibrosis. J Mol Med (Berl). 2012;90:895-910